information on the Fletcher Factor Deficiency

Fletcher Factor Deficiency in Cardiac Anesthesia A Case Report

Citation:

Olivier C. Wenker, David H. Yawn, Gerald M. Lawrie: Fletcher Factor Deficiency in Cardiac Anesthesia A Case Report. The Internet Journal of Anesthesiology. 1997. Volume 1 Number 4.

Introduction

Fletcher-factor deficiency (Fletcher-trait) was first described by Hathaway et al. in 1965 1. The asymptomatic clotting defect is characterized by a prolonged partial thromboplastin time APTT, normal prothrombin time PT and bleeding time. In 1973 and 1974 other authors identified Fletcher-factor as plasma prekallikrein 2 3. The coagulation disorder is considered as very rare and as clinically non-significant 4. We describe for the first time the management of anticoagulation in a patient with Fletcher-factor deficiency undergoing cardiopulmonary bypass for coronary artery bypass graft surgery.

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Fletcher-Factor Deficiency

Wenker O, Yawn D, Lawrie G: Fletcher-Factor Deficiency in Cardiac Anesthesia. ... The impact of Fletcher-factor deficiency on thrombelastography is not known. ...

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Fletcher Factor Deficiency in Cardiac Anesthesia A Case Report

Fletcher Factor Deficiency in Cardiac Anesthesia A Case Report. Olivier C. ... The impact of Fletcher-factor deficiency on thrombelastography is not known. ...

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229000

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Journal of Clinical Investigation -- Fletcher factor deficiency. A ...

Fletcher factor deficiency. A diminished rate of Hageman factor activation caused by absence of ... Fletcher factor-deficient plasma is deficient in ...

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KLKB1 - kallikrein B, plasma (Fletcher factor) 1

Fletcher factor deficiency, source of variations of the activated partial ... thromboplastin antecedent ( PTA, factor XI) deficiency, Fletcher trait ( plasma ...

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Factor Deficiencies, Uncommon (Lab Test Information from ARUP Consult)

ARUP Consult: The Physician's Guide to Laboratory Test Selection and Interpretation provides instant, point-of ... Deficiency of prekallikrein (Fletcher ...

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